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neurokey

ABOUT NEUROKEY

Neurokey is a Europe-based biotech company that develops first-in-class drugs for the critical care segment. It was founded in 2007.

Neurokey addresses a pressing market need for emergency medication that can increase survival rate and reduce the risk of lasting neurological damage in critical care patients.

The four founders of Neurokey all have extensive knowledge of critical care, which they have gained from years of first-hand experience as practising doctors. Their in-depth understanding of physicians’ needs in the segment is the cornerstone of Neurokey product development.

Neurokey is located in the centre of Medicon Valley, one of the biggest biotechnological and pharmaceutical clusters in Europe.

OUR VISION

Neurokey wants to become a leading drug development company in the critical care field.

The drugs under development will one day help countless patients suffering from the effects of debilitating and potentially fatal cardiovascular and neurological diseases. Neurokey will be first-to-market with reliable, efficient and easily administered medication that will increase the survival rate for these patients and dramatically minimise the risk of permanent neurological damage.

THE NEUROKEY R&D APPROACH

Neurokey is building a portfolio of drugs under development for the critical care segment. Neurokey products are based on both original ideas and in-licensing from other companies, institutions and universities.

Neurokey drug candidates are innovative, first-in-class products. Neurokey R&D is committed to going further than simply creating incremental improvements on existing marketed drugs.

Pushing the boundaries of existing research creates a dynamic that can better lead to technological and market breakthroughs. Ultimately, this will ensure that future patients get the best possible treatment for their critical condition.

IPR PORTFOLIO

Neurokey already has an impressive IPR platform protecting its core development projects. Neurokey will continue to broaden its IPR portfolio in accordance with overall company IP strategy.

NEUROKEY INVESTORS

SEED Capital:

• Start-up/early stage focused investor
• Experience from +50 health care and IT start-up companies


Novo Ventures:

• International health care-focused VC investor
• Offices in Copenhagen, London, San Francisco
• Current portfolio ~35 companies (US, EU, early stage to NASDAQ listed)
• Experience in start-up of clinical development stage companies

LATEST NEWS

June 3rd 2008 - Neurokey welcomes new Director of Clinical Operations

Malene Weis comes from a position as Director of Clinical Development in Osteologix and has worked in biotech and pharmaceutical companies for more than 15 years. As Director of Clinical Operations, she will be a significant driver of the process towards the upcoming clinical trials.

July 2nd 2008 - Director of Preclinical Development appointed

Keld Fosgerau leaves a position as Manager, Senior Research Scientist at Rheoscience to join Neurokey. His more than 10 years of industry experience within drug discovery and pharmacology research, preceded by a PhD, constitutes a significant strengthening of Neurokey’s project management and preclinical development capabilities.

August 1st 2008 - New CEO prepares transition into clinical development company

We are happy to announce the appointment of Charlotte Videbaek as new CEO of Neurokey as of August 1st 2008. Charlotte Videbaek brings two decades of neurological expertise: 12 years in academia (MD, DMSc, Specialist in Neurology) and 8 years in the pharma industry (Novartis Pharma AG and Hoffmann-La Roche). She leaves her position as Head of Department for International Clinical Research in Neurology at H. Lundbeck to join Neurokey.

The attraction of a CEO of Charlotte Videbaek’s caliber is a milestone in Neurokey’s growth and, with the additition of her significant expertise in clinical development, it embodies the company’s transformation into a clinical development company.

Charlotte Videbaek succeeds Jacob Gotfredsen who as co-founder and CEO through the initial start-up fase and series A fund-raising has been instrumental in Neurokey’s current success. Jacob Gotfredsen continues as part of the executive management as Chief Business Officer.

CONTACT US

Information:
E-mail: info@neurokey.com
Tel.: +45 7070 2204


Charlotte Videbæk, CEO
E-mail: charlotte.videbaek@neurokey.com
Tel.: +45 7070 2201
Mob: +45 2789 5305


Jacob W. Gotfredsen, CBO
E-mail: jacob.gotfredsen@neurokey.com
Tel.: +45 7070 2205
Mob: +45 2789 5307


Uno Jakob Weber, CSO
E-mail: uno.weber@neurokey.com
Tel.: +45 7070 2202
Mob +45 2818 0182


Contact neurokey

Malene Krahl

You can contact me via us to , or reach us at the following address:

Neurokey A/S
Diplomvej 372, 1st floor
DK – 2800
Lyngby
Denmark


Asphyxia

Asphyxia, or suffocation, can be divided into perinatal asphyxia and non-perinatal asphyxia. Perinatal asphyxia is a birth complication that may leave babies mentally/physically impaired, whereas non-perinatal asphyxia most often is a result of drowning accidents, poisonous gasses or fires.

Cardiovascular disease

Collective designation of diseases affecting the heart or blood vessels. It includes, but is not limited to, arteriosclerosis, coronary artery disease, heart valve disease, arrhythmia, heart failure and hypertension.

Clinical trial

A clinical trial (synonyms: clinical studies, research protocols, medical research) is a research study on patients or healthy volunteers, and it may be designed to assess the safety and efficacy of a novel therapy.

Heart attack

Acute myocardial infarction, commonly known as a heart attack, is a serious, sudden and potentially life-threatening medical emergency. It occurs when the blood supply to a part of the heart is interrupted, causing death and scarring of the local heart tissue. Since the area affected may be large or small, the severity of heart attacks varies.

Hypothermia

Definitions vary, but in the context of NeuroKey’s research and development, hypothermia is defined as a person’s body temperature being below 36.5°C (97.7°F) rectally measured.

Hypothermia therapy

Medical treatment where patients have their body temperature lowered to 36.5°C (97.7°F) or below for hours or days. The actual therapeutic temperature may be as low as 32.0°C (89.6°F), but target temperature and length of treatment depend on the actual disease.

Stroke

Acute neurological injury whereby the blood supply to a part of the brain is interrupted, either by a clot in the artery or if the artery bursts. As a result, the part of the brain perfused by that artery no longer receives oxygen carried by the blood. The oxygen depleted brain matter dies causing cessation of various functions. Stroke is a medical emergency and can cause permanent mental and physical impairment or even death. It is the third leading cause of death and adult disability in the US and European.

Sudden cardiac arrest

Sudden cardiac arrest is an abrupt and unexpected loss of heart function. Patients suffering sudden cardiac arrest have frequently, but not necessarily, been diagnosed with heart disease. The large majority of patients experiencing sudden cardiac arrest dies, especially if they are not in proximity of a hospital.

Target temperature

The optimal body temperature (core temperature) for patients being subjected to hypothermia therapy. Different diseases may require different target temperatures but target will rarely exceed 36.0°C (96.8°F) or fall below 32.0°C (89.6°F).

Traumatic brain injury

TBI occurs when a sudden trauma causes brain damage. TBI can result from a closed head injury or a penetrating head injury. Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. Outcome can be anything from complete recovery to permanent disability or death.

Ventricular fibrillation

Ventricular fibrillation is a disruption of the normal heart rhythm that frequently leads to cardiac arrest. If it continues for more than a few seconds, blood circulation will cease, as evidenced by lack of pulse, blood pressure and respiration, and death can occur.

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